BAK and BAX form a multiprotein complex to drive mtDNA efflux and caspase-independent cell death | Science

The apoptotic regulators BAX and BAK, once activated, form homo-oligomers to trigger mitochondrial outer membrane permeabilization (MOMP), activating the apoptosome and caspases. Activation of BAX-BAK without apoptosome activation triggers sustained ...

Source: https://www.science.org/doi/10.1126/science.aea2181