A trapped catalytic product acts as molecular glue for innate immune signalosome assembly | Science

Innate immune systems of living organisms are essential for host defense. Central to these systems is the Toll/interleukin-1 receptor (TIR) domain, an evolutionarily conserved module. From antiphage systems in prokaryotes to innate immune systems in ...

Source: https://www.science.org/doi/10.1126/science.aef3150