Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program | Science

Mechanisms by which primary tumor cells acquire metastatic capability through metabolic and signaling adaptations are currently poorly understood. We demonstrate that tumor-intrinsic ceramide metabolism, amplified by dietary fat, initiates colorectal ...

Source: https://www.science.org/doi/10.1126/science.adw8520